Vol. 15, Issue 1 (2026)

In this study, the effect of smoking on the concentrations of some important element ions in blood samples of a group of smokers was studied. These elements are (chloride ion, potassium ion, calcium ion, and sodium ion). Fifty blood samples were taken from smokers and 50 blood samples from non-smokers. The Erma EL 120 Electrolyte Analyzer device was used, which works by the ISE method “ion selective electrode” with a sample volume of less than 90 µl. It measures Na, K, Cl, Ca and Li ions. Automatic calibration after 4 hours or before the analysis (two-point), calibration with each analysis (one-point). Age was taken into consideration in addition to the smoking period, and the concentrations of the target element ions in the study were compared in the blood samples of smokers with the concentrations of ions in the blood of the control group, which included blood samples of non-smokers. The results of this study showed that there was a decrease in the concentration of calcium ion in the blood samples of smokers, as well as a decrease in the concentration of chloride ions, while the concentration of potassium ion and sodium ion were not affected in comparison with the blood samples of non-smokers. This was shown by the statistical studies conducted in this study, which were identical to previous studies in this field.