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Vol. 14, Issue 5 (2025)

Resistance / resilience to Haemonchus contortus infection: Comparison between Garole and Sahabadi sheep

Author(s):
Gautam Bordoloi, Anupam Brahma, Supradip Das, Ananta Hembram and Ruma Jas
Abstract:
Resistance / resilience to Haemonchus contortus infection was compared between Garole and Sahabadi sheep in terms of faecal egg count (FEC) and some haemato-biochemical parameters. Twelve Garole and twelve Sahabadi sheep were divided into control (N = 6) and infected (N = 6) groups. Infected groups of both breeds were orally challenged with 500 H. contortus larvae. Faecal egg count and Percent changes in haematological (Hb, PCV, TEC and TLC), serum protein concentration (total protein, albumin and globulin), serum enzyme activity (ALP, AST and ALT) and mineral concentration (Ca, P, Fe and Zn).
FEC was significantly (P<0.01) lower in Garole sheep up to 27 DPI compared to Sahabadi sheep and subsequently, on 30DPI no H. contortus eggs was found in faecal sample of the infected Garole sheep. The percent decline in Hb concentration, PCV (%) and total erythrocyte count (TEC) was consistently higher (P<0.05) in Sahabadi sheep than the Garole sheep and the Percent increase in total leucocyte count (TLC) was higher (P<0.05) in Garole sheep. Percent reduction in serum proteins (TSP, SA and SG) and mineral concentration (Ca, P and Fe) and Percent increase in serum enzymes (ALP, AST and ALT) activities were significantly (P<) higher in Sahabadi sheep compared to Garole sheep. The results of the present study indicated that the Garole sheep were comparatively more resistant to H. contortus than the Sahabadi sheep in terms of FEC and some haemato-biochemical parameters.
Pages: 89-95  |  67 Views  40 Downloads


The Pharma Innovation Journal
How to cite this article:
Gautam Bordoloi, Anupam Brahma, Supradip Das, Ananta Hembram, Ruma Jas. Resistance / resilience to Haemonchus contortus infection: Comparison between Garole and Sahabadi sheep. Pharma Innovation 2025;14(5):89-95.

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