Author(s): Devaki Devi B, Sai Krishna N, Shameem Jaha SK, Lakshmi Bhavani T, Chandra Kala I, Gershom Suvarna Raju D and Siddhardha L
Abstract: Oral Mouth Dissolving Films (OMDFs) represent an innovative drug delivery system designed for rapid disintegration and absorption in the oral cavity without the need for water. These thin, flexible strips improve patient compliance, particularly in paediatric, geriatric, and dysphagic populations. OMDFs offer advantages such as fast onset of action, bypassing of first-pass metabolism, accurate dosing, ease of transport, and enhanced bioavailability. They are formulated using hydrophilic polymers, plasticizers, and taste-masking agents, and are manufactured through techniques like solvent casting or hot-melt extrusion. OMDFs are widely used for systemic and local drug delivery and are gaining popularity due to their convenience, cost-effectiveness, and versatility. With growing market demand and ongoing research, OMDFs are poised to become a preferred alternative to traditional oral dosage form[1]
