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Vol. 13, Issue 1 (2024)

Role of progesterone, relaxin, C - reactive protein during gestation and whelping in crossbred bitch

Author(s):
C Das, PM Barua, D Borpujari, A Das, PJ Nath, M Dutta, M Dasgupta, M Hazarika and S Tamuly
Abstract:
Background: Detection of pregnancy and prediction of whelping time are important for reproductive management in canine. The present study was aimed to study the role of certain blood biochemical profile during gestation viz. progesterone, relaxin and C - reactive protein in detection of pregnancy and whelping time in bitch.
Methods: A total of twenty (20) pregnant crossbred bitches presented to the Veterinary Clinical Complex, Khanapara, Guwahati were selected for the study. The gestational length was divided into first, second and third phase consisting 0(day of mating)-20 day, 21-40 day and 41 days to term (day of whelping). Blood samples were collected to estimate serum progesterone, relaxin, and C - reactive protein using ELISA on 0 (day of mating), 10th, 20th, 30th, 40th, 50th day of gestation and on the day of whelping.
Result: The mean serum progesterone level increased from 10th day (29.97±0.54ng/ml) to 30th day (40.42±0.57ng/ml), while decreasing from 40th day of gestation (35.60±0.33) and recorded lowest (1.66±0.25 ng/ml) on day of whelping. The mean serum concentration of relaxin gradually increased from 10th day (0.39 ±0.03ng/ml) till 50th day of gestation (5.54 ±0.39ng/ml). On day of whelping it dropped to 3.71 ±0.86 ng/ml. The mean serum level of C - reactive protein increased from the 0 day (5.15±0.20 mg/L) to 40th day (86.27±1.55 mg/L) of gestation which decreased then from 50th day gestation (57.95±2.37) and on the day of whelping recorded as 11.62±2.32 mg/L. The mean serum concentration of progesterone, relaxin and C - reactive protein significantly (P< 0.01) differed between days of gestation in crossbred bitches.
Pages: 138-141  |  380 Views  213 Downloads


The Pharma Innovation Journal
How to cite this article:
C Das, PM Barua, D Borpujari, A Das, PJ Nath, M Dutta, M Dasgupta, M Hazarika, S Tamuly. Role of progesterone, relaxin, C - reactive protein during gestation and whelping in crossbred bitch. Pharma Innovation 2024;13(1):138-141.

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