Vol. 12, Issue 1 (2023)

Author(s):
Sanjeevakumar Lalasangi, Suguna Rao, Byregowda SM, Chethan Kumar HB, Shivasharanappa N, Patil SS, Yogisharadhya R, Leena Gowda, Girish MH and Manjunatha Reddy GB

Abstract:
Lumpy skin disease is an important viral disease of cattle and buffaloes caused by lumpy skin disease virus that belonging to genus Capri pox virus. The present study was conducted in Karnataka during the outbreak of LSD to determine the changes in haematological and serum biochemical values of cattle naturally infected with lumpy skin disease virus (LSDV). Blood in EDTA and serum samples were collected from cattle suffering from LSD (n=152) and those which are healthy (n=10). The results of blood parameters in LSD affected animals showed a significant decrease in the total erythrocyte count, haemoglobin and haematocrit values. Serum biochemical analysis showed significant increase in aspartate aminotransferase (p<0.05). In addition, Serum gamma glutamyl transferase, albumin and creatinine values were significantly decreased in serum of infected animals compared to healthy animals. However, there were no significant differences in the other blood and biochemical parameters observed. The results of the current study suggest severe inflammatory process and disease complications such as anorexia and reduced muscle mass associated with natural LSD infection. These findings may help in developing treatment strategies, identification of biomarkers for early detection and for assessing the prognosis LSD.