Vol. 12, Issue 1 (2023)

Author(s):
DVK Yadav, S Bharathi, VD Prasad and GV Naidu

Abstract:
The sparing effect of Dexmedetomidine, Butorphanol, Ketamine combination (group I) and Xylazine, Butorphanol, Ketamine combination (group II) induction on isoflurane for elective Ovariohysterectomy in twelve bitches (dogs) was studied. The dose rates of drugs required for quick induction of general anaesthesia in group I were found to be Dexmedetomidine @ of 6 µgm/kg b.wt, Butorphanol @ 0.1 mg/kg b.wt and Ketamine @ 4mg/kg b.wt. and in group II, it was Xylazine @ 0.6 mg/kg b.wt, Butorphanol @ 0.1 mg/kg b.wt and Ketamine @ 4mg/kg b.wt. The quality of induction, physiological, cardiovascular parameters, time taken for extubation and time taken for total recovery from anaesthesia were recorded and studied. The mean vaporizer setting for maintenance and total quantity of isoflurane consumed was lower in group II compared to group I. It is concluded that Butorphanol and Ketamine combination with Xylazine had more sparing effect on Isoflurane when compared to Butorphanol and Ketamine with Dexmedetomidine on isoflurane in dogs that underwent elective Ovariohysterectomy.