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Vol. 10, Issue 4 (2021)

Simple and rapid RP-HPLC determination of nimesulide in tablets

Ravshankhon Makhmudov and Furkat Yunusov
The present investigation describes a fast and simplified RP-HPLC method for the evaluation of nimesulide in tablets. The method is specific, accurate, precise, and ensures good reproducibility. The sample was analyzed using Acetonitrile (ACN): Ethanol: Water in the ratio of 40:40:20 as a mobile phase at a flow rate of 1.0 ml/min and detection at 276 nm. The retention time for nimesulide was found to be about 3.4, and a recovery from tablet was 99%. The method can be used for the fast and simple quantitative estimation of nimesulide in tablets.
Pages: 01-03  |  1042 Views  307 Downloads

The Pharma Innovation Journal
How to cite this article:
Ravshankhon Makhmudov, Furkat Yunusov. Simple and rapid RP-HPLC determination of nimesulide in tablets. Pharma Innovation 2021;10(4):01-03. DOI: 10.22271/tpi.2021.v10.i4a.6437

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