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Vol. 10, Issue 3 (2021)

Quantification of total phenolic content, total flavonoid content and evaluation of in vitro free radical scavenging activities in Ficus religiosa Linn.

Author(s):
Sushma Ghadigaonkar, AG Reddy, B Kalakumar, M Lakshman and U Rajkumar
Abstract:
This present work was carried out to quantify the total phenolic and total flavonoid content and to investigate the antioxidant activity free radical scavenging activities of leaf of extracts of Ficus religiosa (Peepal). Leaf extracts of Ficus religiosa was prepared by Soxhlet extraction and various extracts were used for in vitro assays. The extraction yields of Ficus religiosa were ranged from 0.98- 10.15 g/50h (w/w) on dry weight basis. The qualitative phytochemical studies revealed presence of alkaloid, saponin, flavonoid, tannin, carbohydrates, and glycosides in different extracts of Ficus religiosa leaf. The results indicated the presence of higher phenolic and flavonoid content in aqueous leaf extracts of Ficus religiosa. It was observed that FRLE contained appreciable amount of TPC (19.97-62.93 µg GAE/mg) and TFC (29.88-135.95 µgQE/mg) as well as exhibited good DPPH radical scavenging activity (10.31-10.99 µg/ml) and nitric oxide radical scavenging activity (10.63-16.0199µg/ml). The results of the present investigation clearly demonstrated the significant variations in antioxidant properties of different solvents extract of Ficus religiosa leaves. It can be concluded from results that Ficus religiosa extracts were good source of natural antioxidants.
Pages: 84-88  |  914 Views  518 Downloads


The Pharma Innovation Journal
How to cite this article:
Sushma Ghadigaonkar, AG Reddy, B Kalakumar, M Lakshman, U Rajkumar. Quantification of total phenolic content, total flavonoid content and evaluation of in vitro free radical scavenging activities in Ficus religiosa Linn.. Pharma Innovation 2021;10(3):84-88.

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