In silico insights into isoflavone reductase (IFR) in Glycine max: Phylogenetic, structural and functional perspectives
Author(s):
Kanika Sharma, Meenu Khurana, Rupinder Kaur Virk and Rupinderjeet Kaur
Abstract:
Soybean (Glycine max) is an globally as well as industrially important oilseed crop that provides several important dietary components but faces growth challenges under various stresses, that cause production and economic losses. Isoflavone reductase (IFR) is a key enzyme controlling isoflavone synthesis and widely involved in response to various stresses. It plays a crucial role in plant defence by contributing to isoflavanoid biosynthesis, a key component of soybean immune response. This study employs in silico approaches to analyze IFR proteins in different types of plants ranging from food crops to medicinal plants providing insights into their phylogenetic relationship and also study the interactions of Isoflavone reductase from Glycine max to elucidate its mode of action. The findings of the study revealed that IFR is highly conserved protein as it plays a very important and significant role in isoflavonoid biosynthesis. Furthermore, it laid the foundation of reinforcing IFR’s involvement in plant growth, development and stress responses.
How to cite this article:
Kanika Sharma, Meenu Khurana, Rupinder Kaur Virk, Rupinderjeet Kaur. In silico insights into isoflavone reductase (IFR) in Glycine max: Phylogenetic, structural and functional perspectives. Pharma Innovation 2021;10(3):1031-1035.