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Vol. 9, Issue 6 (2020)

Synthesis, characterization and evaluation of 3-acetylindole derivatives evaluating as potential anti-inflammatory agent

Author(s):
Nitish Kumar and Amrita Parle
Abstract:
In the present study a series of novel 3-acetylindole derivatives were synthesized by reacting 3-acetylindole and benzaldehyde. The synthesized 3-acetylindole derivatives were characterized physico-chemically and by spectral (IR and 1H-NMR) analysis. All the synthesized compounds were screened for their in-vitro anti-inflammatory activity by inhibition of the albumin denaturation technique using diclofenac as standard. The results revealed that most of the compounds have better activity as compared with the standard diclofenac.
Pages: 461-467  |  412 Views  125 Downloads


The Pharma Innovation Journal
How to cite this article:
Nitish Kumar, Amrita Parle. Synthesis, characterization and evaluation of 3-acetylindole derivatives evaluating as potential anti-inflammatory agent. Pharma Innovation 2020;9(6):461-467.

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