Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 8, Issue 6 (2019)

Stability study of Vijaysaradi ghanvati used in the management of type 2 diabetes (Madhumeha) - with respect to baseline microbial diagnostic modalities

Author(s):
Sachin Kumar Sharma, Alankruta R Dave, MS Cholera and Vasundhara Sharma
Abstract:
Background: Diabetes Mellitus is one of the most serious health problems in the 21st century. In Ayurveda disease Diabetes Mellitus can be correlated with Madhumeha. Madhumeha (Type 2 Diabetes) is included in the Ashtamahagadas caused by the involvement of all three Doshas and ten Dushya. Lots of single and compound drugs have been described in Ayurveda for the management of Madhumeha (Type 2 Diabetes). From such mentioned medicines a compound formulation has been made named Vijaysaradi Ghanvati which is found to be very effective in the management of Madhumeha (Type 2 Diabetes). In this formulation Heart wood of Vijaysar (Pterocarpus marsupium), Fruit of Haritaki (Terminalia chebula), Fruit of Amlaki (Emblica officinalis), Fruit of Vibhitaki (Terminalia belerica), Panchang of Kiratatikta (Swertia chirata), Leaves of Patolpatra (Trichosanthes dioica), Rhizome of Katuki (Picrorhiza kurroa), Fruit of Gokshur (Tribulus terrestris), Root of Musta (Cyperus rotundus), Heart wood of Swetcandan (Santalum albam), Stem and Root of Daruharidra (Berberis aristata), Root of Usira (Vetiveria zizanioides) were taken.
Materials and Methods: Sample of Vijaysaradi Ghanvati was prepared and studied to check microbial contamination at regular time intervals. Vati was stored in plastic container during different climatic conditions were studied at regular intervals of 1 month for a period of 11 months to analysis Mycological findings and presence of bacteriological findings by Wet mount preparation and Gram stain test respectively.
Results: Sample was subjected to the microbiological study from the date of the preparation to the date of last microbiological study. No any contaminations were found in microbiological study.
Discussion: Hence the present Study was carried out to observe the stability study of Vijaysaradi Ghanvati with respect to Microbial Contamination of sample prepared and store in different climatic conditions and temperature. Thus a baseline Microbial profile was studied at regular interval of 1 month for total 1 year & 2 month (i.e. time for consumption of prepared drug). At the end of study it was found that sample was not showed presence of any Microbes.
Conclusion: In microbiological study, Vati container has not present of microbes after 14 months of preparation sample, even in different climate and temperature, shows its stability and good shelf life. Hence in present study the stability test of Vijaysaradi Ghanvati with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.
Pages: 1121-1127  |  406 Views  71 Downloads


The Pharma Innovation Journal
How to cite this article:
Sachin Kumar Sharma, Alankruta R Dave, MS Cholera, Vasundhara Sharma. Stability study of <em>Vijaysaradi ghanvati</em> used in the management of type 2 diabetes (<em>Madhumeha</em>) - with respect to baseline microbial diagnostic modalities. Pharma Innovation 2019;8(6):1121-1127.

Call for book chapter