An experimental study on the antidote effect of maricha (Piper nigrum Linn) kashaya in vatsanabha (Aconitum ferox) induced toxicity
Kavitha KV and Sudheendra V Honwad
Mahavishas are a group of highly potential drugs and Vatsanabha is one among them. which is a cardiac poison by modern concept and main toxic principles are aconitine, pseudoaconitine. The substance which are counteracting or neutralizing the effect of poison are considered as antidotes, in Ayurveda prathyoushada concept can be compared with this. In Kriyakoumudi text Maricha kashaya mentioned as an antidote for Vatsanabha seed poisoning. To evaluate the antidote effect in Vatsanabha poisoning TED dose of Maricha kashaya is used. biochemical parameters, haematological parameters, histopathological studies were compared. Vatsanabha showed mild to moderate toxicity in liver, which have been reversed by Maricha kashaya in TED dose which is suggestive by results of biochemical parameters, and histopathological studies.
How to cite this article:
Kavitha KV, Sudheendra V Honwad. An experimental study on the antidote effect of maricha (<em>Piper nigrum </em>Linn) kashaya in vatsanabha (<em>Aconitum ferox</em>) induced toxicity. Pharma Innovation 2018;7(7):893-898.