Comparative evaluation of romifidine-ketamine and xylazine-ketamine induction combination for isoflurane anaesthesia in cattle
Venkatgiri, Dilipkumar D and Shivaprakash BV
The study was conducted in 12 clinical cases presented to TVCC, Bidar. Twelve animals were randomly divided in to two groups viz., Group-I and Group-II consisting of six animals in each group. Group –I animals received Romifidine (10µg/kg) intravenously, 10minutes later ketamine was given @3mg/kg body weight intravenously for induction of anaesthesia. In Group-II animal’s xylazine (0.1mg/kg) was administered intravenously, 10minutes later ketamine was given @3mg/kg body weight intravenously for induction of anaesthesia followed by immediate intubation, maintaenance of anaesthesia was done under isoflurane in both the groups. Anaesthetic combinations were compared by clinic physiological, haemodynamic and haematological observations. The induction and recovery were smooth and uneventful in both the groups. Induction was quicker in group-I animals. Physiological and haemodynamic parameters like heart rate, respiratory rate, rectal temperature, mean arterial pressure and haemoglobin oxygen saturation were fluctuated within normal limit.non significant bradycardia in group-I. Intermittent apnoea was observed in all animals, frequency was higher in group-I. heamoglobin packed cell volume and total erythrocyte count were decreased non-significantly in both the groups. Nuetrophilia and relative lymphocytopenia was recorded in both the groups. In conclusion romifidine as pre-anaesthetic for ketamine and isoflurane anaesthetic maintenance is a better combination than xylazine –ketamine and isoflurane anaesthetic mainatnanace in cattle.
How to cite this article:
Venkatgiri, Dilipkumar D, Shivaprakash BV. Comparative evaluation of romifidine-ketamine and xylazine-ketamine induction combination for isoflurane anaesthesia in cattle. Pharma Innovation 2017;6(8):114-118.