Vol. 6, Issue 4 (2017)
Impact of fertigation type on the anti-dermatophytic potential and its minimal inhibitory drug concentration of petals of Rosa bourboniana. Desp
P Rajesh Babu, M Gopalakrishnan, R Harini, M Asrar Sheriff, AK Sultan Mohideen and T Sekar
The present study is aimed to explore the potentiality of organic (combination of vermicomposts prepared from cow dung. press mud, tea dust and vegetable wastes in the ratio of (1:1:1:1) and inorganic fertilizer (NPK, 1:2:1 ratio) amendment on the antidermatophytic potentials of petals of Rosa bourboniana for the first time. The plot with no supplements is taken as the control. The experiment was executed in a complete randomized block design (CRBD). An extrapolated value of 6 tons ha -1 of amendments were used during the overall 330 days of cultivation period. At the end of the cultivation the petals were extracted with four solvents and were evaluated for anti-dermatophytic screening by disc diffusion method. Dermatophytic strains included in the study were Trichophyton rubrum, Trichophyton mentagrophyte, Candida albicans, Epidermophyton floccosum and Trichophyton tonsurans procured from the Microbial Type Culture Collection and Gene bank (MTCC), Institute of Microbial Technology (IMTECH), Chandigarh, India. Clotrimazole was used as the positive control. All the four extracts showed anti-dermatophytic activity against the selected strains except for the chloroform extract against Trichophyton rubrum and that of ethanolic fractions against Candida albicans. Highest activity was observed with the hexane fractions against Trichophyton tonsurans with 22 mm of zone of inhibition. Highest anti-dermatophytic activity was observed with the samples from the vermicompost treated plots. In the minimal inhibitory drug concentration study the samples from the organic plot was strong enough to inhibit the growth of dermatophytic strains at low concentrations comparing to the other two samples.
How to cite this article:
P Rajesh Babu, M Gopalakrishnan, R Harini, M Asrar Sheriff, AK Sultan Mohideen, T Sekar. Impact of fertigation type on the anti-dermatophytic potential and its minimal inhibitory drug concentration of petals of Rosa bourboniana. Desp. Pharma Innovation 2017;6(4):95-102.