Vol. 6, Issue 10 (2017)
Antimicrobial potential of different solvents leaf extract of Millettia peguensis against selected pathogens
D Packiyalakshmi, P Athilakshmi, S Gayathri, P Karthiga, R Thiri Bhuvaneswari and G Manikandan
Millettia peguensis is commonly known as Moulmein rosewood, is a legume tree species in the genus Millettia belongs to the family Fabaceae. It is native to Lower Burma and Siam. This is a relatively rare tree as compared to Pongam that is very similar looking, but more common in India. The powdered leaf was successively extracted with Hexane, Chloroform and Petroleum ether through soxhlet apparatus. Antimicrobial activity was studied using agar well diffusion method at various concentrations (100mg/ml, 150mg/ml and 200mg/ml) of extracts. These extracts inhibited severely on the growth of microorganisms and implied antimicrobial activity on Gram-positive bacteria; Bacillus cereus, Staphylococcus aureus and Micrococcus mucilaginosus, gram-negative bacteria; Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli and Klebsiella terrigena, Fungi; Candida albicans, Candida glabrata and Candida sp. Petroleum ether leaf extracts were effectively tested against microorganisms and also compared with standard antibiotic (Amphicilin; 500mg/ml). The maximum antimicrobial activities were obtained with maximum zone of inhibition in petroleum ether (200mg/ml) extract followed by chloroform and hexane. The results indicated that the leaf extracts might be utilized as natural drug for the treatment of several infectious diseases by microorganisms.
How to cite this article:
D Packiyalakshmi, P Athilakshmi, S Gayathri, P Karthiga, R Thiri Bhuvaneswari, G Manikandan. Antimicrobial potential of different solvents leaf extract of Millettia peguensis against selected pathogens. Pharma Innovation 2017;6(10):119-124.