Vol. 4, Issue 8 (2015)

Author(s):
Maryana M Vasylechko

Abstract:
The purposeof this study was to carry out a comparative analysis of signs and symptoms by scale EHRA, type of paroxysm flow and structural-functional state of the myocardium in the patients with new-onset atrial fibrillation (NOAF) depending on the presence of insulin resistance. 114 patients (66 male, 48 female; age: 66 ± 10 years) with NOAF and metabolic syndrome (MS) by ATP III (2001) were observed. Depending on the endogenous insulin (EI) levels patients were divided into 3 groups: group 1 consisted of 44 patients with normal plasma EI levels; group 2 consisted of 31 patients with reactive hyperinsulinemia (HI); group 3 consisted of 39 patients with spontaneous HI.
In old age under NOAF with reactive and spontaneous HI permanent form of AF is formed more often with an increased risk of thrombotic events and increasing complaints associated with arrhythmias by a scale EHRA and progression of chronic heart failure (CHF). The increase in the metric and volume left heart indexes is accompanied by an imbalance between the sympathetic and parasympathetic links autonomic nervous system (ANS), the formation of the adrenergic type of AF with increasing average HR, decrease RMSSD and increase of SDANN parameters of HRV.