Abstract:In the present-day research, natural compound become the hot point of study for the safe and effective drug. Flavonoids are one of the important secondary plant metabolites. Flavone and flavonols are the major class of flavonoids, important biologically active plant-derived natural compounds. So search of new and plant-derived natural flavone and flavonols, having radical scavenging activity is of major attention to the scientists now. The present review includes 63 new examples of naturally occurring flavones and flavonols having antioxidant potential reported during the period of 2005 to Jan, 2015. These flavones and flavonols are found either as aglycones or as glycosides, comprising flavones, flavone glycosides, flavonols and flavonol glycosides. The main topics addressed are source, structure, antioxidant activity. The review cites 78 references.