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Vol. 4, Issue 10 (2015)

Retrospective investigation of the clinicopathological relationship in the identification of granulomatous skin diseases

Author(s):
Retrospective investigation of the clinicopathological relationship in the identification of granulomatous skin diseases
Abstract:
Introduction and Background: A varied category of diseases known as granulomatous cutaneous disorders is defined by the formation of granulomas, which are clusters of inflammatory cells in one specific area. The purpose of this research is to examine the relationship between clinical symptoms and histological findings in the diagnosis of granulomatous cutaneous diseases.
Materials and Methods: Granulomatous cutaneous lesions were the focus of this five-year retrospective investigation of patients seen at a tertiary healthcare facility. This study was conducted at the department of Pathology, Institute of Medical Sciences and Research, Mayani, Maharashtra, India from October 2014 to September 2015. The results of the physical examination, as well as the patient's history and current condition, were documented in the clinical record. In every instance, the biopsy specimens were examined histopathologically. The purpose of this research was to find out how well histopathological findings matched up with clinical diagnoses.
Results: The research enrolled 150 individuals who were thought to be suffering from granulomatous cutaneous diseases. Sarcoidosis (45 cases) and granulomatous dermatitis (40 cases) accounted for 70% (105 cases) of the non-infectious granulomatous conditions, while cutaneous tuberculosis (30 cases) and leprosy (15 cases) accounted for 30% (45 cases) of the infectious granulomatous disorders. The study discovered that clinical and histological diagnoses were highly concordant, with granulomatous dermatitis showing 90% concordance and sarcoidosis showing 100%. A high concordance rate of 93% was also seen for leprosy and cutaneous tuberculosis.
Conclusion: The significance of histological examination in establishing a diagnosis of granulomatous skin illnesses is highlighted in this study. Although granulomatous dermatitis has a lower concordance rate than other dermatologic conditions, it is important to be attentive when making a differential diagnosis because this condition might mimic others. Accurate diagnosis, treatment plans, and proper patient management are all greatly aided by histopathology.
Pages: 103-106  |  32 Views  18 Downloads


The Pharma Innovation Journal
How to cite this article:
Retrospective investigation of the clinicopathological relationship in the identification of granulomatous skin diseases. Retrospective investigation of the clinicopathological relationship in the identification of granulomatous skin diseases. Pharma Innovation 2015;4(10):103-106.

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