Vol. 3, Issue 5 (2014)

Author(s):
S CH Raghu Kumar and Mothika B Mallikarjuna Rao

Abstract:
Background and Objectives: The surgical correction of nasal septal deviation is known as septoplasty and is a treatment that is frequently performed. Intraoperative hemodynamics, postoperative recovery, and problems like nausea, vomiting, or emerging agitation might be impacted by the choice of anesthetic agent. Common anesthetics desflurane and propofol have different pharmacodynamic and pharmacokinetic characteristics. Propofol and desflurane anesthesia were compared for septoplasty surgery in terms of efficacy, recovery time, hemodynamic stability, and postoperative results. Materials and Methods: A prospective, randomized, controlled experiment involved sixty patients, aged 18 to 60 years, with ASA physical status I or II, scheduled for elective septoplasty under general anesthesia. The study included 30 patients, who were split into two equal groups: Group P received intravenous propofol for induction and maintenance, and Group D received intravenous desflurane for induction and maintenance. Adverse postoperative symptoms, including nausea, vomiting, and agitation, together with intraoperative hemodynamic parameters, anesthetic duration, emergence time, and extubation time, were recorded. When we used Student's t-test and Chi-square test to do the statistical analysis, we thought a p-value of less than 0.05 was statistically significant. Results: Both groups had similar demographics, surgical times, and hemodynamics at the start of the procedure. Intraoperative hemodynamic stability was more consistent and less erratic in Group P than in Group D. The desflurane group had a noticeably lower emergence time (6.2±1.1 min) compared to the propofol group (8.5±1.4 min, p<0.001), while the time it took to extubate was similar in both groups. Compared to the desflurane group, which had 23.3% postoperative nausea and vomiting, the propofol group had 6.7% (p = 0.04). Neither group reported any major adverse events. Conclusion: A safe and efficient anesthetic for septoplasty can be provided by either propofol or desflurane. Quicker emergence is possible with desflurane, although better intraoperative hemodynamic stability and less postoperative nausea and vomiting are benefits of propofol. It is possible to personalize the anesthetic selection process based on patient attributes, surgical needs, and postoperative recuperation objectives.