Abstract:Aim: The objective of the present investigation was to assess the frequency and antibiotic susceptibility pattern of
S. aureus that was isolated from a variety of clinical specimens of patients.
Method: Approximately 200 clinical specimens were collected and inoculated on sheep blood agar, chocolate, and mannitol salt agar. Incubated in an aerobic atmosphere at 35 °C for 18-24 hours. In order to ascertain antibiotic susceptibility, the Kirby-Bauer disc diffusion method was implemented.
Results: The investigation involved the collection of a total of 200 samples. Age categories 1-10 (15%), 11-20 (16%), 21-30 (32%), 31-50 (21%) and 51-70 (16%) were used to divide the samples. There were 146 males and 54 females. The age group with the highest Staph aureus isolate was 21-30 (33%), followed by 31-50 (23%) and 1-10 (9%). The highest isolate of Staph aureus from clinical specimens was more prevalent in males than in females due to gender. The prevalence of Staph aureus varied significantly among distinct clinical specimens. Swabs accounted for 32% of the isolates, while tips and pus accounted for 22% and 18%, respectively. Vancomycin exhibited the highest susceptibility level of Staph aureus, with Ciprofloxacin (60%), Septrin (59%), Erythromycin, and Amikacin (65) being equally effective. However, Amoxicillin exhibited the maximum resistance level (43%), followed by Tetracycline (38%), and Gentamycin (21%).
Conclusion: The most antibiotics that were discovered to provide consistent sensitivity were Erythromycin, Ciprofloxacin, and Vancomycin. Clinicians will be able to establish antibiotic treatment approaches by determining the prevalence and antibiotic sensitivity pattern of Staph aureus.