Vol. 1, Issue 2 (2012)

Author(s):
K.P. Sampath kumar*, Debjit Bhowmik, Shweta Srivastava, Shravan Paswan and A.S. Dutta

Abstract:
Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimizing side effects. Oral drug delivery system represents one of the frontier areas of controlled drug delivery system. Such a dosage forms having a major advantage of patient compliance. Sustained release dosage forms are designed to release a drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects  Now a days as very few drugs are coming out of research and development and already existing drugs are suffering the problem of resistance due to their irrational use specifically in case of drugs like antibiotics. Hence, change in the operation is a suitable and optimized way to make the some drug more effective by slight alteration in the drug delivery. Sustained Release is also providing promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body.