Volume 4, Issue 7
Role of Oxidative Stress and Antioxidant Status in Preeclampsia
Asha N S, Anju Varghese
Abstract: The present study was undertaken to provide further evidence about the role of oxidative stress and antioxidant status in preeclampsia. 50 preeclamptic patients in the third trimester and 50 normal healthy subjects in the third trimester with normal blood pressure and no complications were recruited for the present study by convenient sampling technique. S.MDA and erythrocyte glutathione concentration were estimated by standard methods described in the literature. Data was analyzed by SPSS 20.0. Values are expressed as mean ± SD. P- value <0.05 was taken as significant. We conclude that both the oxidative stress and anti-oxidants have a role in preeclampsia. We recommend further detailed studies in this area with higher sample size and more biomarkers.
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