Volume 4, Issue 3
Development of composition and some technology aspects of frozen-dried medicine on the basis of bee venom
Author: R. I. Skrypnik-Tikhonov, P. S. Sirota, A. I. Tikhonov, M. S. Almakaev,
L. G. Naumenok, N. V. Begunova
Abstract: Proceeding from the literary data and physical and chemical properties of substance of bee venom and auxiliary substances the rational composition of frozen-dried medicine on the basis of bee venom and its optimal рН level has been experimentally confirmed. Auxiliary substances increasing the mass of frozen-dried medicine and its compactness, providing the isotonicity of the solution and comfort at intramuscular introduction of the medicine have been chosen. The optimal filling volume of ampoules and bottles that provides the quality of frozen-dried medicine satisfying to the requirements of specification has been recommended.
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