Volume 4, Issue10
Study of rheological properties of rectal suppositories with phenothiazine
Author: Olena S Romelashvili
Abstract: Rheological properties of suppositories on the basis of the original substance phenothiazine-1-methyl-4[((2-phenethyl) amino) carbonyl]pyridinium iodide exhibiting pronounced analgesic and antipyretic activity, stimulating effect on the factor of natural resistance – phagocytosis, moderate anti-inflammatory activity and assigned to low-toxic substances have been studied. The dependence of structural viscosity and shear stress of phenothiazine suppository mass on the gradient of shear rate at different temperatures has been studied. Temperature of phenothiazine suppository mass preparation and dispensing has been determined.
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