Volume 3, Issue 1
Phytochemical research of Galium aparine L. Lipophilic complex and study of its antibacterial activity
Author: Olga V. Goryacha 1, Tetyana V. Ilyina 1, Alla M. Kovalyova 1, Nataliya V. Kashpur 2
1. The National University of Pharmacy, Kharkov, Ukraine
2. I.I. Mechnikov Institute of Microbiology and Immunology of Academy of Medical Sciences of Ukraine, Kharkov, Ukraine
Abstract: From Galium aparine L. herb lipophilic complex of biologically active substances had been obtained for the first time. By means of TLC and chromatography-mass-spectrometry the composition of lipophilic complex had been studied. 3 Sesquiterpenoids, squalene, 7 aromatic compounds, higher alkanes and their derivatives, fatty acids have been identified and quantified; presence of chlorophylls, carotenoids and 2 iridoids had been established. Antibacterial and antifungal activity of Galium aparine herb lipophilic complex and degree of these activities have been studied for the first time. Test-strains of S. aureus, P. aeruginosa and C. albicans were highly sensitive and B. subtilis is moderately sensitive to lipophilic complex of Galium aparine herb.
Fig: Chromatographic profile of Galium aparine herb lipophilic complex
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