Volume 3, Issue 1


Topographic characteristics of the level of osteoprotegerin in cadaver blood of patients with copd affected by lung tuberculosis


Author: N.V.Obukhova 1*

1. The Donetsk State Medical University named after M.Gor’kiy, Ukraine

Abstract: Patients with chronic obstructive pulmonary disease (COPD) with recent lung tuberculosis (TB) were studied on the question of regional level of osteoprotegerin (in cadaver blood from various vascular regions in the study of postmortem). It was found out that patients with COPD had no significant effect of the recent TB and it didn’t influence the level of the investigated indicator in various vascular regions. Thus, among COPD patients the osteoprotegerin level in induced sputum, according to previous studies, is formed by the local cytokine synthesis (at the tissue level of the bronchi), but not by means of increasing its level in the blood entering the pulmonary circulation through the inferior vena cava (IVC).


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