Volume 2, Issue 5
Synthesis and Characterisation of 3-Acetylindole Derivatives and Evaluation of Their Anti-Inflammatory and Anti-Microbial Activity
Author: Loveleen Verma *, Dr. Sharad Wakode
Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research
(DIPSAR), Sector-3, Pushp Vihar, New Delhi-110017, India.
Abstract: A series of 3-Acetylindole derivatives were synthesised by a three step process by reacting 3-acetylindole and aromatic aldehydes in the first step. The purity and structure confirmation of the synthesised compounds were done by TLC and 1H-NMR. The compounds were evaluated for anti-microbial and anti-inflammatory activity. The test compound LV-5 showed highest anti-inflammatory activity and the test compounds LV-5, LV-6 and LV-8 showed highest anti-microbial activity.
Download Full Article: Click Here
Support Us
If you are interested in supporting our work and would like to contribute, you are welcome to mail me at jpbr.anil@gmail.com or at info@thepharmajournal.com it will be a great help and will surely be appreciated.
