Volume 2, Issue 11
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Caused by Viruses: The need of Combined Anti-Infective Chemotherapy
Author: Ya. О. Dziublyk
Abstract: The aim of the study was to evaluate the effectiveness of combined antibacterial and anti-viral therapy of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), caused by viruses.
Materials and Methods: 56 patients with AECOPD, triggered by acute respiratory viral infection (ARI) were enrolled. All patients were administered amoxicillin/clavulanate 1000 mg twice daily plus vitaglutam 90 mg once daily (1st group) or amoxicillin/clavulanate 1000 mg twice daily (2nd group). All patients were examined using physical and laboratory tests. Biological samples of all patients were also tested in order to identify viral and bacterial pathogens.
Results: In patients of 1st group we observed shorter use of antibiotic, lower rate of infectious complications and faster clinical and laboratory recovery. The data of pharmacoeconomical analysis indicated that the cost of antimicrobial therapy was lower in the 1st group as well.
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