Vol. 9, Issue 6 (2020)

Author(s):
Banhishikha KAR, Ayan Kumar KAR, Subhabrota Majumdar and Beduin Mahanti

Abstract:
Rosacea is a chronic inflammatory condition of the central facial skin affecting the blood vessels and pilosebaceous units. It is a common skin state that causes redness and visible blood vessels particularly in facial region. Generally, there are two types of rosacea based on either “performed” clinical or patient adopted analysis of rosacea. The etiology and pathophysiology are poorly understood. It may also produce small, red pus-filled bumps. These signs and symptoms may flare up for weeks to months and then go away for a while. In some circumstances it can be mistaken for acne, other skin problems or natural rosiness. Rosacea has a variety of triggers: lead to deliver of diverse mediators like endothelial cells, keratinocytes, macrophages, T1 and T17 cells. In addition, these trigger factors directly spread to the nurvous system, lead to the reflection of rosacea injury. Rosacea can affect anyone but it is most common in middle-aged women who have light skin. There is no permanent cure for rosacea, but treatment can control and reduce the signs and symptoms. Patients generally complaints of flushing and blushing and sensitive skin, and their skin may be especially irritated by any kind of topical preparations. Rosacea has a variety of triggers; however, they may be unnoticed by the patient. Validated treatments and drugs approved by the FDA which includes ivermectin, oxymetazoline hydrochloride, azelaic acid, topical metronidazole, and oral tetracyclines, in particular minocycline and doxycycline, brimonidine etc. Here, the aim of present strategies to sum up the modern concept along with diagnosis and address a symptom-based approach in the management of patients with rosacea.