Vol. 8, Issue 8 (2019)

Author(s):
Priyanka, Sukhdeep Vohra, Satyavir Singh and Arun K Sangwan

Abstract:
The present study was conducted to detect the status of anthelmintic resistance of commonly used anthelmintic drugs against gastrointestinal nematodes in goats of village Satnali, district Mahendergarh, Haryana. Sixty goats with eggs per gram of more than or equal to 150 were divided into four groups i.e. G1, G2, G3 and G4 of 15 animals each. Group G1, G2 and G3 were treated with fenbendazole @ 10 mg/kg b.wt. orally, morantel @ 20 mg/ kg b.wt. orally and ivermectin @ 0.4 mg/kg b.wt. subcutaneously, respectively. Group G4 served as untreated control. Faecal egg counts of goats were ascertained on day of treatment (0 day) and 12^th day post treatment (PT) of all groups by the modified McMaster technique. Pooled faecal cultures were made to recover infective larvae on day 0 and 12 PT. Results revealed that fenbendazole reduced the faecal egg counts by 14.23% with upper and lower confidence levels as 39.10% and 20.29%, respectively indicating severe anthelmintic resistance. Morantel and ivermectin reduced the faecal egg counts by 60.87% and 89.72%, respectively on 12th day PT with upper and lower confidence levels as 83.20% and 8.86% and 97.11% and 63.51%, respectively indicating moderate anthelmintic resistance against both drugs. The post-treatment coproculture showed larvae of Haemonchus contortus and Strongyloides sp. Thus, the present study revealed presence of multiple anthelmintic resistance of fenbendazole, morantel and ivermectin against H. contortus in goats of unorganized sector in Mahendergarh, Haryana.