Antibiotics are chemical substances produced by various species of microorganisms and other living systems that are capable of inhibiting the growth of or killing bacteria and other micro organism. Among the very few remarkable events in the history of microbial diseases, antibiotic discovery is the one. With the advancement of scientific research, one is almost free from deadly infectious diseases and the surgery of medical science is no longer a desperate gamble with human life This is primarily due to the antibiotic discovery. As a result of it people can live safely and healthily for a longer period. The meaning of the word antibiotic in Greek is “against life”.
Objectives: The objectives of this work is to study the use of antibiotics in paediatrics intensive care unit at a tertiary care hospital and to study the commonly used antibiotics in paediatrics intensive care unit based on age group also to observe the duration of antibiotics prescribed.
Materials and methods: It was a prospective observational study done over a period of six months (May 2017 to November 2017) in Rajah Muthiah medical college hospital, chidambaram, Tamilnadu. This study was approved from Institutional Human Ethics committee. A 100 samples were collected from the hospital to study the use of antibiotics used in patients of both gender and age group below 5 years admitted in PICU of RMMCH. Patients of age group below 5 years and those who are not willing is excluded.
Results: The results were obtained from 100 patients admitted at Pediatrics intensive care unit of RMMCH who were enrolled into the study after fulfilment of the selection criteria described above on obtaining consent from the same. Among the 100 patients, majority were male (64%) as compared to female patients (36%). Overall, 60 patients belongs to age group 0 to 1 year (12months) accounting for 60% of total. A total of 14 patients belongs to 1 to 2 years accounting for 14% of total. A total of 12 patients belongs to 2 to 3 years accounting for 12% of total. A total of 4 patients belongs to 3 to 4 years accounting for 4% of total. A total of 10 patients belongs to 4 to 5 years accounting for 10% of total patients included in this study.
Conclusion: Antibiotics resistance is one of the major threat and it is alarming that no newer antibiotics are available in research and development pipeline in recent years. According to WHO, india is one of the country where antibiotic resistance is predominant. Our study shows that maximum number of patients belongs to 0-1 years accounting for 60% of the total number patients admitted in the study population, 64% patients were male children and 36% were female children. In this study most commonly diagnosed disease condition is Lower respiratory tract infection. Out of 100 patients 60 patients ie, 60% were diagnosed with LRTI.