Vol. 8, Issue 7 (2019)
Efficacy of combination of orally administered ivermectin (Neomac) and topically applied amitraz (RIDD® solution) against generalized demodicosis in dog
Manu M, K Unnikrishnan and Mousumi Bora
Canine demodicosis is a parasitic skin disease caused by an overpopulation of the host-specific follicular mites of the genus Demodex. Most cases of canine demodicosis are caused by Demodex canis, although two other species of demodex mites are reported. Localized demodicosis is a common mild and benign self-limiting disease. In contrast, generalized demodicosis is a serious and potentially life-threatening disease. Most cases of generalized demodicosis are juvenile in onset and develop in dogs less than 1 year of age. The present study was aimed to determine the efficiency of oral ivermectin and topical amitraz individually and a combination of both the drugs against generalized demodicosis in dogs. Study was conducted among 12 animals which were divided into three groups with four animals in each group. The different treatment regimens were adopted for 45 days. After 45 days of therapy, dogs treated with combination therapy showed quick recovery than the dogs treated with ivermectin or topical amitraz alone indicating the efficiency of combination therapy.
How to cite this article:
Manu M, K Unnikrishnan and Mousumi Bora. . The Pharma Innovation Journal. 2019; 8(7): 38-41.