Vol. 8, Issue 2 (2019)
Preparation and evaluation of phytosomes containing ethanolic extract of leaves of Bombax ceiba for hepatoprotective activity
Sarita Karole, Girendra Kumar Gautam and Shailesh Gupta
The plants of Bombax ceiba are traditionally used as home remedy in the treatment of jaundice, spleen enlargement and in some literature as Hepatoprotective activity. In the current days, the majority of the widespread diseases and nutritional disorders are treated with natural medicines. The efficiency of any herbal medication is reliant on the delivery of efficient level of the therapeutically active compound. But a harsh limitation exists in their bioavailability when administered orally or by topical applications. Phytosomes are lately introduced herbal formulations that are superior absorbed and as a result produced superior bioavailability and actions than the conformist phyto molecules or botanical extracts. The ethanolic extract of phytosome was prepared in soya lecithin. Soya lecithin has antioxidant activity. Evaluation of phytosomes for solubility study, entrapment efficiency, transition temperature, particle size and size distribution, optical microscopic study, zeta potential, transmission electron microscopy, stability studies, in vitro dissolution studies, and FTIR study. In vitro antioxidant activity of phytosomes determined by DPPH model. Combination of soya lecithin and Bombax ceiba can result in synergistic effect, Synergistic effect measure with free radical scavenging activity use DPPH model.
How to cite this article:
Sarita Karole, Girendra Kumar Gautam and Shailesh Gupta. . The Pharma Innovation Journal. 2019; 8(2): 22-26.