Vol. 8, Issue 1 (2019)

Author(s):
Nutan, Nitin Kumar and Gaurav Saxena

Abstract:
Mammalian tumour cells display resistance to chemotherapy and its severe side effects diminishes the clinical usefulness of a huge variety of anticancer agents. Plant-derived compounds manifest many beneficial effects, furthermore be able to probably inhibit several stages of cancer. In the present study, we endeavored to take advantage of bioactive compounds of Hemidesmus indicus, so we investigated their antioxidant and antiproliferative properties on colon cancer cell lines HCT116. The preliminary phytochemical screening of ethanolic extract showed the presence of significant secondary metabolites. Our findings infer that the potential bioactive compounds of plant has significantly inhibited the growth of colon cancer cells and its extract can be applied as adjuvant medicines in combination regular chemotherapeutic agents.