Vol. 7, Issue 9 (2018)

Author(s):
Seth P, Bhattacharya A, Agarwal S, Tripathi RM, Thahriani A and Gianchandani P

Abstract:
Collagen is the main protein of connective tissue and is the most abundant protein in human body, making up about one quarter i.e 25% to 35% of the whole-body weight and helps to maintain the integrity of tissues^. It is a large family of triple helical proteins present throughout the body. It is the principal tensile element of tissues in vertebrates, and is also main component of ligaments and tendons. Protein comprises roughly 20% of body mass out of which 25-35% is composed of collagen. Out of this 90% is type I collagen and rest is of other types. Hence an adult of 70 kg contains more than 1 x 10 type I collagen monomers.