Vol. 7, Issue 8 (2018)

Author(s):
Sarvan Kumar, KK Jakhar, Vikas Nehra and Satyavir Singh

Abstract:
This study was envisaged to elucidate the clinico-pathological aspects viz haematological, serum biochemical and oxidative stress parameters in diarrhoeic buffalo calves. Investigation was carried out on 21 buffalo calves (6 healthy and 15 buffalo calves affected with diarrhoea). Haematological studies revealed significant decrease in value of haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC). There was no significant variation in values of erythrocyte indices i.e. mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC) and mean corpuscular volume (MCV). Significant increase in total leukocytic count (TLC) was observed in calves affected with diarrhoea. Serum biochemical studies revealed that although there were increase in values of total protein, serum albumin, serum globulin in diarrhoeic buffalo calves but that was not significant. However, there was decrease in albumin: globulin ratio in diarrhoeic buffalo calves. Significant increase in activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) was noticed in diarrhoeic buffalo calves whereas, non-significant increase in activity of lactate dehydrogenase (LDH) was observed. Studies of oxidative stress parameters showed that there was significant decrease in activity of superoxide dismutase (SOD), glutathione-s-transferase (GST) and glutathione reductase (GR) whereas significant increase in activity of catalase was noticed in diarrhoeic buffalo calves. The present study elucidated that there are alterations of haemato-biochemical and oxidative stress parameters in buffalo calves showing diarrhoeic symptoms.