Vol. 7, Issue 3 (2018)

Author(s):
Ramadevi S, Kaleeswaran B, Suman T, Thirumalaivasan, Murugesan R

Abstract:
Pedalium murex (L.) has long been treating as a medicinal plant for various diseases like disorders of urinary systems, renal injury and other problems and also it contains an abundance of phytochemical compounds. Therefore, it is important to screen the total phenolics (TP) and flavonoids content (TF), its potent antioxidant capacities using standard methods to find out the novel antioxidant supplements to food and used in pharmaceutical industries. The whole plant of P. murex L. was used to prepare the Aqueous extract (AQEP) and ethyl acetate extract (EAEP) was adopted with boiling and Soxhlet extraction methods respectively. Furthermost, it has been screened for the presence of phenolic and flavonoid compounds and its antioxidant capability. The presence of phytocompounds was increasing the antioxidant properties to terminate free radicals in the body. It was determined by UV method, DPPH for free radical scavenging activity (2, 2-diphenyl-1-picrylhydrazyl) and 2, 20-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), respectively. From the results, EAEP has highest phenolic (283.16±7.18 mg GAE/g extract), flavonoid (521.00±1.44 mg GAE/g extract) than AQEP. Ethyl acetate extract (IC₅₀6.07±1.94) has more scavenging activity than aqueous extract (IC₅₀10.09±1.68) compared to positive control Rutin and BHT. From the results, we concluded that EAEP has support as medicine for treating of infectious diseases and also to eradicate free radicals to protect the human from various diseases due to the presence of high content of phytocomponents.