Vol. 7, Issue 1 (2018)
Haemato-pathological studies of subchronic profenofos toxicity in broiler birds
A Kafle, DC Roy, TN Upadhayaya and Sushree SM
The study was conducted to assess the toxic effects of Profenofos, an organophosphate pesticide on haematological and histopathological picture of broiler birds following subchronic exposure. A total of 20 day old chicks, 10 in each group were taken for the study. Group I served as control while Group II as treatment group. One tenth of LD50 dose, was orally administered daily for 60 days to test group (Group II). The treated birds showed significant escalation of all the haematological parameters with the exception of Lymphocyte count. The histopathological examination showed various alterations in different organs in group II, manifested by periportal fibrosis in liver, congested blood vessels of the lung and brain and coagulative necrosis with hydropic degeneration in the Kidney. From the present study it can be concluded that subchronic exposure of profenofos cause significant changes in haematology as well as histopathology in broiler birds.
How to cite this article:
A Kafle, DC Roy, TN Upadhayaya and Sushree SM. . The Pharma Innovation Journal. 2018; 7(1): 19-23.