Vol. 6, Issue 9 (2017)

Author(s):
Priyansha Raj Sinha and Amit Alexander Charan

Abstract:
Parkinson’s is one of the most horrendous disease affecting 1% of the adult population above the age of 60 and 4% over the age 85 ^[1]. This disease is chronic and progressive in neurodegeneration causing dopaminergic neurons in Substantia nigra region of the mid brain to die which ultimately leads to decrease in dopamine production in our brain. Though any direct cause of this disease has not been identified yet, but many genetic mutations and environmental factors are found to be related to it. The diagnosis depends on family genetic history and disease symptoms. Dopamine is a neurotransmitter which controls certain notable functions of body including movement, memory, sleep, attention and learning. Due to plummeted production of dopamine, a Parkinson’s patient encounters several symptoms like tremor, bradykinesia, rigidity, postural instability .