Vol. 6, Issue 3 (2017)

Author(s):
Tamanna Talreja, Mangesh Kumar, Parmendra Sirohi and Tribhuwan Sharma

Abstract:
The present study was designed to test the efficacy of two medicinal plants–Cissus quadrangularis and Achyranthes aspera in the management of weight loss in humans. For this, frequency of obesity among the different age group people of Bikaner was surveyed and enlistment of volunteers for herbal treatment of obesity based on Achyranthes aspera and Cissus quadrangularis preparations was done. By using Achyranthes aspera and Cissus quadrangularis powder preparation of edible nutraceuticals their organoleptic test and evaluation of shelf life was done. Based on the result of these tests, formulations and the doses were decided. To clarify the anti-obesity efficacy of these plants experiment was designed on mice model. After getting satisfactory results, doses were decided for human and given to the patients enlisted as volunteers in the supervision of registered medical practitioner. These subjects were examined once a week during 10 weeks of study period and their Anthropometric as well as physiological measurements were recorded and Analytical and statistical analysis of data was done. Results showed that Cissus and Achyranthes brought about a significantly greater weight loss than placebo during the study period in obese individuals and a significant improvement in the lipid profiles and anthropomorphic profiles of study participants was seen.