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Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
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Vol. 6, Issue 1 (2017)
Spirometry changes in stable COPD patients treated with roflumilast
Author(s):
Iryna Savelikhina, Mykola Ostrovskyy, Oleksandr Varunkiv, Mariana Kulynych-Miskiv and Kseniia Ostrovska
Iryna Savelikhina, Mykola Ostrovskyy, Oleksandr Varunkiv, Mariana Kulynych-Miskiv and Kseniia Ostrovska
Abstract:
COPD is a progressive condition involving chronic inflammation and parenchymal destruction with resulting airflow limitation. COPD is associated with worsening airflow limitation over time and increased frequency of COPD exacerbations, leading to increased mortality and morbidity worldwide. The effects of COPD extend beyond the lungs, as multiple comorbidities may occur with COPD, including cardiovascular disease, diabetes mellitus, osteoporosis, depression, and pneumonia.
COPD is a progressive condition involving chronic inflammation and parenchymal destruction with resulting airflow limitation. COPD is associated with worsening airflow limitation over time and increased frequency of COPD exacerbations, leading to increased mortality and morbidity worldwide. The effects of COPD extend beyond the lungs, as multiple comorbidities may occur with COPD, including cardiovascular disease, diabetes mellitus, osteoporosis, depression, and pneumonia.
Roflumilast is a selective inhibitor of the enzyme phosphodiesterase-4 that targets the systemic inflammation associated with COPD. Roflumilast has a variety of anti-inflammatory effects including decreasing inflammatory mediators and the expression of cell surface markers and inhibition of apoptosis.
Pages: 07-09 | 1553 Views 110 Downloads
How to cite this article:
Iryna Savelikhina, Mykola Ostrovskyy, Oleksandr Varunkiv, Mariana Kulynych-Miskiv, Kseniia Ostrovska. Spirometry changes in stable COPD patients treated with roflumilast. Pharma Innovation 2017;6(1):07-09.
Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
Main Menu
Special Issue
Copyright Form
Identifier
The Pharma Innovation Journal
