The aim of the present study is to evaluate antidiabetic activity of methanolic extract of Actinidia deliciosa fruit in alloxan induced albino Wister rats.
Methods: Actinidia deliciosa fruit extract or metformin was administered to the rats orally for seven days. Levels of Blood Glucose, Triglycerides, Cholesterol, HDL cholesterol, SGOT and SGPT were used to evaluate its antidiabetic effects in Albino Wister rats.
Results: Blood glucose, Triglycerides, Cholesterol, HDL cholesterol, SGOT and SGPT levels were significantly increased in alloxan induced diabetic rats to compare to the normal group. After seven days treatment with Actinidia deliciosa extract showed the significant decrease in the diabetic control group and metformin also showed a significant decrease in diabetes.
Conclusion: Our results suggest that the methanolic extract of Actinidia deliciosa fruit clearly demonstrated the antidiabetic activity in an experimental model of rats.