Vol. 5, Issue 6 (2016)

Pharmacological studies included the screening of finding the optimal composition of the gel by antiexudative action, choosing the optimal amount of gel, the membrane-stabilizing effect of the gel and research of the toxicological characteristics of the "Propolis" gel.

It has been found that the gel contains PPHM 2,0% and AA, and possesses a maximum antiexudative effect. The optimum amount of the "Propolis" gel for skin application is equal to 12.5 mg/cm2. It has been proved that the "Propolis" gel has a pronounced membrane-protective effect, and it is its main distinction fromthe comparing medication – the "Scinoren" gel 15%. As for acute toxicity parameters the "Propolis" gel refers to a class of practically non-toxic substances.