Vol. 5, Issue 4 (2016)
In silico- internet and analogue based drug design of new anticancer agent
Ajay S Bisht, Divya Juyal
As now a day there is development and importance of computational chemistry including molecular docking and a SAR study which deals with pharmacophore based drug design approach. As the methodology linked with modification of the target based drug discovery by using sophisticated computational tools which are generally not very easy to understand and also got many incompatibility issues with many operating systems (OS) and other system configurations. Thus, the present study deals with the SAR (Structure Activity Relationship) study and pharmacophore based drug design approaches with the use of free internet based tools which are much user friendly and almost compatible with any platform. Here, in this paper attempts are made to design some daunomycin analogues using pharmacophore study as more potent or equivalent anticancer agents and their drug like properties, toxicity, metabolic sites and some other parameters that are predicted by the free internet based tools.
How to cite this article:
Ajay S Bisht, Divya Juyal. In silico- internet and analogue based drug design of new anticancer agent. The Pharma Innovation Journal. 2016; 5(4): 14-19.