Vol. 5, Issue 11 (2016)

Author(s):
O V Marynchak

Abstract:
Features of chronic hepatitis C (CHC) course, it extrahepatic manifestations depend on immunopathological reactions. Immune system is unable to eliminate the virus, to prevent serious complications and consequences in case of CHC. However, the level of the main pro-inflammatory and anti-inflammatory cytokines in patients with CHC and concomitant diabetes mellitus (DM) has been scarcely studied. The article presents the data on the features of the immune response such as IL-2 and IL-4 content in the treatment of CHC with concomitant DM. The use of such drugs as Dialipon and Livolactum in the comprehensive basic treatment of CHC with concomitant DM promotes faster regression of clinical laboratory symptoms, the balance of cytokines towards normalization of IL-2 and IL-4 content in comparison with the patients who did not undergo this combined treatment.