Vol. 5, Issue 11 (2016)

Author(s):
HM Havryliuk and NV Kosylo

Abstract:
Hysterectomy is one of the most common surgeries on the uterus with increasing number post-hysterectomy pathological manifestations. A comprehensive examination and surgical treatment of 60 women of reproductive age with uterine myoma who had hysterectomy with uterine annexes preservation have been carried out. The control group consisted of 20 somatically healthy women. To assess metabolic homeostasis disorders we have studied certain parameters of hormonal homeostasis and the range of certain blood lipoproteins. The results of the analysis of hormonal profile indicators in women with post-hysterectomy syndrome symptoms in 12 and 36 months after surgery revealed in 36.6% the statistically significant increase of prolactin level, 46.6% had hypestrogenism and 41.6% of patients had the signs of hypoandrogenaemia, confirmed by laboratory criteria. Patients with a low estrogens saturation of the organism suffered from hyperlipidemia, which was noticed in 55.6% of women. These changes make preconditions for the progression of metabolic dysfunction in women and initiate the development of metabolic syndrome.