Vol. 4, Issue 9 (2015)

Author(s):
Vaskul NV

Abstract:
Hepatitis C in different countries is a serious problem of modern Infectology. Despite the large amount of studies devoted to the study of HCV-infection, the mechanisms of progression of chronic hepatitis C in patients with concomitant pathology today are not quite clear. The aim of this study is to examine the clinical-laboratory peculiarities of chronic hepatitis C, depending on the presence of cardiovascular risks. It was determined that in patients with chronic hepatitis C with concomitant total cardiovascular risk there were significantly higher levels of hyperbilirubinemia and increase of cytolytic syndrome more severe violation of T-cell immune response to antigens of HCV infection that is manifested by the increased levels of IL-4 and TNF-α and the decreased levels of IL-2, and significantly higher levels of viral load.