Vol. 4, Issue 8 (2015)
Effects of lesion of Amygdaloid nuclei on blood immunocytes in male albino rats
Nilotpal Mandal, Goutam Dutta, Anandaraj Goswami, Tusharkanti Ghosh
The regulatory role of nervous system on immune system has been emphasized by several investigators. In the present study, the role of basolateral nucleus (BLP), central nucleus (CeA) and medial nucleus (MeA) of amygdala on Total count (TC) of WBC, Differential Count (DC) of WBC and Arneth count of nutrophil were studied after two weeks of lesion of these nuclei of amygdala by electrolytic method in separate groups of rats. The results of these lesioned rats were compared with that of control and sham operated rats. Though the TC of WBC was not altered after lesion of any one of the three amygdaloid nuclei. The percentage of lymphocyte was significantly increased in BLP lesioned rat and decreased in CeA lesioned rats that of the control and sham operated rats. The percentage of neutrophil was significantly decreased in BLP lesioned rat compared to that of control and sham operated rats after two weeks of operation. In Arneth count the percentage of 3 lobed and 4 lobed neutrophils was significantly decreased while the percentage of 6 lobe and 7 lobed was significantly increased in BlP lesioned rats compared to that of control and sham operated rats after two weeks of operation. It appears from this study that BLP and CeA of amygdale exhibit a modulatory role on blood immunocytes and this immunomodulatory role of different nuclei of amygdale is not similar.
How to cite this article:
Nilotpal Mandal, Goutam Dutta, Anandaraj Goswami, Tusharkanti Ghosh. . The Pharma Innovation Journal. 2015; 4(8): 102-106.