Vol. 4, Issue 7 (2015)
Principles of pathogenetic therapy of diabetic gastroparesis
The therapeutic effectiveness of α-lipoic acid preparations and benfotiamine in treating symptoms of gastroparesis in patients with diabetes mellitus was evaluated. Pathogenetic interrelationships among increasing concentration of peripheral myelin protein and a decrease in the motor-evacuation function of the stomach were determined. The results of a three-month course of pathogenetic therapy demonstrate the effectiveness of combination therapy which is not associated with an improved compensation of carbohydrate and lipid metabolism. It is a result of the direct effect of preparations on the investigated metabolic processes and restoration of myelination of the nerve fibers.