Vol. 4, Issue 5 (2015)

Author(s):
Mity Thambi, Tom Cherian

Abstract:
Strychnos-nux-vomica which belongs to the family loganiacea also called Kanjiram is a medium-sized tree. The bark of the plant was under investigation. The bark of the plant was collected and extracted using ethyl acetate solvent. GC-MS analysis was conducted to identify the components present in it. The major components present in this extract were strychnine and brucine. The antibacterial screening of the extract was carried out by disc diffusion method. The extract was tested against four pathogenic bacterial stains of gram positive and gram negative organism. The ethyl acetate extract of Strychnos-nux-vomicashows antimicrobial activity.